The investment casting of titanium alloys is growing in importance and economic value. The reactive nature of these alloys forces the foundry to be more critical in selecting the key materials – the pattern and runner waxes, and the primary and second coat binders, flours and stuccos – used in the process. This paper reviews Wax, Binder and Refractory options available to the investment caster, discusses the factors to be considered when making the selection and provides system recommendations that will enable a foundry to begin investment casting of titanium alloys.